Article
Characteristics of T cell lines established from skin lesions of Behçet's disease.
Journal of dermatological science - 1 May 1997
Mochizuki M, Morita E, Yamamoto S, Yamana S
Abstract excerpt
Hypersensitivity to a streptococcal antigen is postulated to be the pathogenesis of Behçet's disease. We analyzed T lymphocyte-phenotypes infiltrated in cutaneous pustular lesions in Behçet's disease and found that CD4+ T cells were predominant components although CD8+ T cells were also present in the lesion. In addition, we established T cell lines from pustular lesions of the four patients with a streptococcal...
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