Article
[The future of antiviral drugs].
La Revue du praticien - 15 Mar 1997
Moutouh L, Calvez V, Huraux J M
Abstract excerpt
Despite much recent progress, antiviral chemotherapy has still to meet some major challenges: residual cytotoxicity of much antiviral drugs; emergence of viral strains resisting to the most specific antiviral drugs; inability of the most active antiviral drugs to suppress latent viral infections. Several approaches using gene therapy (e.g. hybridons, ribozymes, or dominant negative mutants) might theoretically...
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