Article
Cytotoxic cells are activated in cellular infiltrates of alcoholic chronic pancreatitis.
Gastroenterology - 1 May 1997
Hunger R E, Mueller C, Z'graggen K, Friess H, Büchler M W
Abstract excerpt
BACKGROUND & AIMS: Perforin messenger RNA (mRNA) expression has been shown to be a specific in vivo activation marker for cytotoxic cells. In this study, the contribution of cell-mediated cytotoxicity in the pathogenesis of alcoholic chronic pancreatitis is assessed. METHODS: Tissue sections of patients with alcoholic chronic pancreatitis were analyzed for perforin mRNA expression by in situ hybridization. In a...
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