Article
The genetics and natural history of hereditary colon cancer.
Seminars in oncology nursing - 1 May 1997
Lynch J
Abstract excerpt
OBJECTIVES: To provide an overview of the genetics, natural history, surveillance and management of hereditary colorectal cancer with emphasis on hereditary nonpolyposis colorectal cancer (HNPCC). DATA SOURCES: Published research and review articles, clinical summaries, and personal experience. CONCLUSION: Hereditary factors may account for approximately 10% of colorectal cancer cases. Genes responsible for some...
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