Article
Brain infarction and the clinical expression of Alzheimer disease. The Nun Study.
JAMA - 12 Mar 1997
Snowdon D A, Greiner L H, Mortimer J A, Riley K P, Greiner P A, Markesbery W R
Abstract excerpt
OBJECTIVE: To determine the relationship of brain infarction to the clinical expression of Alzheimer disease (AD). DESIGN: Cognitive function and the prevalence of dementia were determined for participants in the Nun Study who later died. At autopsy, lacunar and larger brain infarcts were identified, and senile plaques and neurofibrillary tangles in the neocortex were quantitated. Participants with abundant...
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