Article
HLA class II antigens DR4 and DQ8 are associated with allergy to hevein, a major allergen of Hevea latex.
Tissue antigens - 1 Jan 1997
Rihs H P, Chen Z, Cremer R, Baur X
Abstract excerpt
In this study we investigated the relationship between HLA class II alleles and the IgE-specific immune response to the 4.7 kDa polypeptide hevein of Hevea brasiliensis, a major latex allergen, 51 individuals with immediate-type latex allergy and 90 controls were examined for the polymorphisms in exon 2 of HLA-DRB1, 3, 4, 5 and DQB1 by sequence-specific oligonucleotide probe typing. 35 (69%) out of 51...
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