Short alleles revealed by PCR demonstrate no heterozygote deficiency at minisatellite loci D1S7, D7S21, and D12S11.

Article

Short alleles revealed by PCR demonstrate no heterozygote deficiency at minisatellite loci D1S7, D7S21, and D12S11.

American journal of human genetics - 1 Feb 1997

Alonso S, Castro A, Fernández-Fernández I, de Pancorbo M M

Abstract excerpt

Short VNTR alleles that go undetected after conventional Southern blot hybridization may constitute an alternative explanation for the heterozygosity deficiency observed at some minisatellite loci. To examine this hypothesis, we have employed a screening procedure based on PCR amplification of th...

Topics

Alleles
Blotting, Southern
Heterozygote
Homozygote
Humans
Minisatellite Repeats
Polymerase Chain Reaction

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