Article
Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo.
Development (Cambridge, England) - 1 Dec 1996
Stainier D Y, Fouquet B, Chen J N, Warren K S, Weinstein B M, Meiler S E, Mohideen M A, Neuhauss S C, Solnica-Krezel L, Schier A F, Zwartkruis F, Stemple D L, Malicki J, Driever W, Fishman M C
Abstract excerpt
As part of a large-scale mutagenesis screen of the zebrafish genome, we have identified 58 mutations that affect the formation and function of the cardiovascular system. The cardiovascular system is particularly amenable for screening in the transparent zebrafish embryo because the heart and bloo...
Topics
- Animals
- Cardiovascular System
- Embryonic Development
- Endocardium
- Heart Defects, Congenital
- Heart Rate
- Hemorrhage
- Mutation
- Myocardial Contraction
- Phenotype
- Zebrafish