Article
No independent associations of LMP2 and LMP7 polymorphisms with susceptibility to develop IDDM.
Diabetes - 1 Feb 1997
Undlien D E, Akselsen H E, Joner G, Dahl-Jørgensen K, Søvik O, Rønningen K S, Thorsby E
Abstract excerpt
Results from a recent study suggested that polymorphisms within the HLA class II genes LMP2 and LMP7 were associated with the susceptibility for developing IDDM, and that this association could not be explained by linkage disequilibrium to HLA-DR or -DQ genes. We typed 285 IDDM patients and 337 HLA-DRB1-DQA1-DQB1 genotypically matched control subjects from an ethnically homogeneous population for both the G/T...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.