Propagation of a Human Herpesvirus from AIDS-Associated Kaposi's Sarcoma

doi:10.1056/nejm199701163360302

Article

Propagation of a Human Herpesvirus from AIDS-Associated Kaposi's Sarcoma

16 Jan 1997

Abstract excerpt

BACKGROUND: Although unique DNA sequences related to gammaherpesviruses have been found in Kaposi's sarcoma lesions, it is uncertain whether this DNA encodes a virus that is able to reproduce. METHODS: We isolated and propagated a filterable agent whose DNA sequences were found to be identical to those of the Kaposi's sarcoma-associated herpesvirus (KSHV). We obtained early-passage spindle cells from skin lesions...

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