Review: preimplantation diagnosis of inherited disease.

doi:10.1007/BF01799159

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Article

Review: preimplantation diagnosis of inherited disease.

Journal of inherited metabolic disease - 1 Jan 1996

Lissens W, Sermon K, Staessen C, Assche E V, Janssenswillen C, Joris H, Van Steirteghem A, Liebaers I

Abstract excerpt

Preimplantation diagnosis of inherited diseases has become possible with the techniques of in vitro fertilization, blastomere biopsy of the 6- to 10-cell embryo and DNA analysis of the single blastomeres. Disease-free embryos are selected for transfer to the uterus, thereby avoiding the need for...

Topics

Alleles
Blastomeres
DNA
Female
Fertilization in Vitro
Genetic Linkage
Humans
Polymerase Chain Reaction
Pregnancy
Prenatal Diagnosis
X Chromosome

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