Article
[Detection and typing of hepatitis C RNA in liver biopsies in comparison with histopathology].
Verhandlungen der Deutschen Gesellschaft fur Pathologie - 1 Jan 1995
Cathomas G, McGandy C E, Terracciano L M, Gudat F, Bianchi L
Abstract excerpt
Total RNA of 55 frozen liver biopsies were extracted and tested for the presence of HCV RNA and the genotype by RT-PCR using primers of the 5' non-coding region and a type specific primer set for HCV genotyping. In paralell, the activity of chronic hepatitis, the stage of fibrosis as well as chracteristic features of chronic hepatitis C were evaluated by conventional histology. HCV RNA was detected in 49 (89.1%)...
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