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Effects of passive immunization against inhibin-peptide on secretion of follicle-stimulating hormone and ovulation rate in ewes carrying the Booroola fecundity gene.

Biology of reproduction - 1 Dec 1996

Wheaton J E, Thomas D L, Kusina N T, Gottfredson R G, Meyer R L

Abstract excerpt

Objectives of the study were to determine whether 1) inhibin negative feedback regulation of FSH secretion is diminished in ewes carrying a copy of the Booroola fecundity (FecB) gene and 2) differential FSH secretion is obligatory for expression of gene-specific differences in ovulation rate (OR). The approach was to compare FSH and ovulatory responses to passive immunoneutralization of inhibin in ewes with and...

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PMID: 8949893
DOI: 10.1095/biolreprod55.6.1351

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effects of passive immunization against inhibin-peptide on secretion of follicle-stimulating hormone and ovulation rate in ewes carrying the Booroola fecundity gene.PMID 8949893Read ↗

Effects of the Booroola Fec gene on ovarian follicular populations in superovulated Romanov ewes pretreated with a GnRH antagonist.Semantic proximity Read ↗

Ontogeny of ovarian follicle development in Booroola sheep fetuses that are homozygous carriers or non-carriers of the FecB gene.Semantic proximity Read ↗

Effect of follicle size and of the FecB Booroola gene on oocyte function in sheep.Semantic proximity Read ↗

Effects of the Booroola gene (FecB) on body weight, ovarian development and hormone concentrations during fetal life.Semantic proximity Read ↗

Concentrations of immunoreactive inhibin in ovarian and peripheral venous plasma and follicular fluid of Booroola ewes that are homozygous carriers or non-carriers of the FecB gene.Semantic proximity Read ↗

Plasma FSH, LH and immunoreactive inhibin concentrations in FecBB/FecBB and FecB+/FecB+ Booroola ewes and rams from birth to 12 months of age.Semantic proximity Read ↗

Highly prolific Booroola sheep have a mutation in the intracellular kinase domain of bone morphogenetic protein IB receptor (ALK-6) that is expressed in both oocytes and granulosa cells.Semantic proximity Read ↗

Effect of exogenous FSH on ovulation rate in homozygous carriers or noncarriers of the Booroola FecB gene after hypothalamic-pituitary disconnection or after treatment with a GnRH agonist.Semantic proximity Read ↗

The effect of the Booroola (FecB) gene on peripheral FSH concentrations and ovulation rates during oestrus, seasonal anoestrus and on FSH concentrations following ovariectomy in Scottish Blackface ewes.Semantic proximity Read ↗

Effect of testosterone and bovine follicular fluid on concentrations of luteinizing hormone and follicle-stimulating hormone in plasma of castrated rams that are homozygous carriers or non-carriers of the Booroola fecundity gene.Semantic proximity Read ↗

Gonadotrophin-releasing hormone and the control of ovulation rate by the FecB gene in Booroola ewes.Semantic proximity Read ↗

Inhibin production in vitro by granulosa cells from Booroola ewes which were either homozygous or non-carriers of a fecundity gene influencing their ovulation rate.Semantic proximity Read ↗

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