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Article

Anaplastic large-cell lymphomas of T-cell and null-cell phenotype express cytotoxic molecules

15 Nov 1996

Abstract excerpt

To further specify the cellular origin and nature of anaplastic large-cell lymphoma (ALCL) and its relationship to other lymphoid neoplasms, particularly Hodgkin's disease (HD), we investigated the presence of cytotoxic molecules in a large well-characterized series of these tumors. For expression of the cytotoxic molecules perforin and granzyme B, in situ hybridization (ISH) and immunohistology were used,...

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Identifiers

PMID: 8916967
DOI: 10.1182/blood.v88.10.4005.bloodjournal88104005

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