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Article

Autoregulation of mariner transposase activity by overproduction and dominant-negative complementation.

Molecular biology and evolution - 1 Apr 1996

Lohe A R, Hartl D L

Abstract excerpt

Genetic studies of the mariner transposable element Mos1 have revealed two novel types of regulatory mechanisms. In one mechanism, overproduction of the wild-type transposase reduces the overall level of transposase activity as assayed by the excision of a nonautonomous mariner target element. This mechanism is termed overproduction inhibition (OPI). Another mechanism is observed in a class of hypomorphic...

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PMID: 8882498
DOI: 10.1093/oxfordjournals.molbev.a025615

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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