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Article

Maternal age effect on early human embryonic development and blastocyst formation

1 Sept 1996

Abstract excerpt

In humans, age-related decline in female fertility can be explained by a reduction in quality either of the older uterus or of the embryos arising from aging oocytes. The aim of this study was to examine the latter hypothesis, using in vitro fertilization (I.V.F.) and coculture of embryos until the blastocyst stage. We determined the blastocyst formation rate ([blastocysts/embryos on day 2]* 100) and the...

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PMID: 8873066
DOI: 10.1002/(sici)1098-2795(199609)45:1<31::aid-mrd4>3.0.co;2-t

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