Article
Genetic divergence of poliovirus strains isolated in the Karachi region of Pakistan.
The Journal of general virology - 1 Dec 1995
Huovilainen A, Mulders M N, Agboatwalla M, Pöyry T, Stenvik M, Hovi T
Abstract excerpt
Seventy-seven wild poliovirus strains isolated from poliomyelitis cases in the Civil Hospital of Karachi in Pakistan in 1989-1993 were selected for partial sequence analysis covering the VP1/2A junction region of the viral genome to study the genetic relationships and epidemiological links between strains. Viral RNA was partially amplified by RT-PCR and sequenced by a solid phase method. Computer analysis...
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