Article
Factor X Stockton: a mild bleeding diathesis associated with an active site mutation in factor X.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jan 1996
Messier T L, Wong C Y, Bovill E G, Long G L, Church W R
Abstract excerpt
A unique blood coagulation factor X variant has been identified in a family with a history of bleeding. Plasma from affected family members had prolonged prothrombin times and activated partial thromboplastin times, low to below normal factor X coagulant activity, and normal factor X antigen leve...
Topics
- Amino Acid Sequence
- Base Sequence
- Binding Sites
- Factor X
- Female
- Hemorrhagic Disorders
- Humans
- Molecular Sequence Data
- Mutation
- Partial Thromboplastin Time
- Pedigree