Article
Increased frequency of apolipoprotein epsilon 2 allele in non-insulin dependent diabetic (NIDDM) patients with nephropathy.
Clinical genetics - 1 Dec 1995
Eto M, Horita K, Morikawa A, Nakata H, Okada M, Saito M, Nomura M, Abiko A, Iwashima Y, Ikoda A
Abstract excerpt
The genetic polymorphism of apolipoprotein E (epsilon 2, epsilon 3 and epsilon 4) is associated with lipid abnormalities. It has been suggested that lipid abnormalities may contribute to the development and progression of kidney diseases, including diabetic nephropathy. Thus, in this study we com...
Topics
- Alleles
- Apolipoprotein E2
- Apolipoproteins E
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Gene Frequency
- Humans
- Phenotype
