Analysis of the VPg-proteinase (NIa) encoded by tobacco etch potyvirus: effects of mutations on subcellular transport, proteolytic processing, and genome amplification.

doi:10.1128/JVI.70.10.7039-7048.1996

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Article

Analysis of the VPg-proteinase (NIa) encoded by tobacco etch potyvirus: effects of mutations on subcellular transport, proteolytic processing, and genome amplification.

Journal of virology - 1 Oct 1996

Schaad M C, Haldeman-Cahill R, Cronin S, Carrington J C

Abstract excerpt

A mutational analysis was conducted to investigate the functions of the tobacco etch potyvirus VPg-proteinase (NIa) protein in vivo. The NIa N-terminal domain contains the VPg attachment site, whereas the C-terminal domain contains a picornavirus 3C-like proteinase. Cleavage at an internal site s...

Topics

Biological Transport
Endopeptidases
Gene Amplification
Genome, Viral
Mutation
Plants, Toxic
Potyvirus
Nicotiana
Viral Proteins

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