Article
Estimation of the prevalence of familial hypercholesterolaemia in a rural Afrikaner community by direct screening for three Afrikaner founder low density lipoprotein receptor gene mutations.
Human genetics - 1 Oct 1996
Steyn K, Goldberg Y P, Kotze M J, Steyn M, Swanepoel A S, Fourie J M, Coetzee G A, Van der Westhuyzen D R
Abstract excerpt
We have determined the prevalence of familial hypercholesterolaemia (FH) in a rural Afrikaner community by means of direct DNA screening for three founder-related Afrikaner low density lipoprotein (LDL) receptor gene mutations. A random sample of 1612 persons, aged 15-64 years, was selected as a subsample of 4583 subjects from an Afrikaner community living in the south-western Cape, South Africa. Participants who...
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