Article
Laboratory diagnosis and molecular epidemiology of an outbreak of hepatitis C virus infection among recipients of human intravenous immunoglobulin in Spain.
Transfusion - 1 Aug 1996
Echevarría J M, León P, Domingo C J, López J A, Elola C, Madurga M, Salmerón F, Yap P L, Daub J, Simmonds P
Abstract excerpt
BACKGROUND: Passive transfer of antibody to hepatitis C virus (HCV) has been thought to occur after infusion of human intravenous immunoglobulin (IVIG), as anti-HCV and/or HCV RNA was commonly found in that product. Recently, however, HCV RNA was detected in the serum of recipients of IVIG. Estab...
Topics
- Adolescent
- Adult
- Aged
- Base Sequence
- Child
- Female
- Genotype
- Hepacivirus
- Hepatitis C
- Humans
- Immunoglobulins, Intravenous
- Male
- Middle Aged
- Molecular Sequence Data
- Polymorphism, Restriction Fragment Length