Article
Heterogeneous Helicobacter pylori isolates from members of a family with a history of peptic ulcer disease.
Gastroenterology - 1 Sept 1996
van der Ende A, Rauws E A, Feller M, Mulder C J, Tytgat G N, Dankert J
Abstract excerpt
BACKGROUND & AIMS: Duodenal ulcer formation in persons infected with Helicobacter pylori correlates with the expression of the cytotoxin-associated gene A (cagA) and the vacuolating cytotoxin (VacA). The aim of this study was to assess the occurrence of cagA and VacA variants among H. pylori isolates. METHODS: H. pylori was isolated from 8 members of one family with a history of peptic ulcer disease (PUD). Each...
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