Article
Strong association of the third hypervariable region of HLA-DR beta 1 with autism.
Journal of neuroimmunology - 1 Jul 1996
Warren R P, Odell J D, Warren W L, Burger R A, Maciulis A, Daniels W W, Torres A R
Abstract excerpt
We reported that the major histocompatibility complex (MHC) including the null allele of the C4B gene and the extended haplotype B44-C30-DR4 is associated with autism. We report now that the third hypervariable region (HVR-3) of certain DR beta 1 alleles have very strong association with autism. The HVR-3 of DR beta 1* 0401 or the shared HVR-3 alleles DR beta 1* 0404 and DR beta 1* 0404 and DR *0101, was...
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