Article
Review of G and P typing results from a global collection of rotavirus strains: implications for vaccine development.
The Journal of infectious diseases - 1 Sept 1996
Gentsch J R, Woods P A, Ramachandran M, Das B K, Leite J P, Alfieri A, Kumar R, Bhan M K, Glass R I
Abstract excerpt
Candidate rotavirus vaccines have been prepared with reassortant strains specifically to protect against the 4 major rotavirus G serotypes (G1 -4). Many studies using P (VP4) genotyping methods have indicated that, worldwide, rotavirus strains of the 4 common G serotypes are each associated with 1 P genotype: GI, G3, and G4 are associated with P[8], and G2 is associated with P[4]. In contrast, G and P genotyping...
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