Donor-specific cellular immune response against human cardiac valve allografts.

doi:10.1016/S0022-5223(96)70250-7

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Article

Donor-specific cellular immune response against human cardiac valve allografts.

The Journal of thoracic and cardiovascular surgery - 1 Aug 1996

Hoekstra F, Knoop C, Vaessen L, Wassenaar C, Jutte N, Bos E, Bogers A, Weimar W

Abstract excerpt

We studied the presence of donor-specific T lymphocytes in explanted human cardiac valve allografts in vivo. From five of seven explants we propagated lymphocyte cultures in an interleukin-2 conditioned medium. Phenotyping revealed the presence of T-cell receptors in more than 95% of the lymphocy...

Topics

Adult
Aortic Valve
Cells, Cultured
Child
Child, Preschool
Culture Media
Cytotoxicity, Immunologic
Histocompatibility Antigens Class I
Histocompatibility Antigens Class II
Humans
Immunity, Cellular
Infant
Interleukin-2
Killer Cells, Lymphokine-Activated
Middle Aged
Phenotype
Pulmonary Valve
Receptors, Antigen, T-Cell

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Open in PubMed

Identifiers

PMID: 8751491
DOI: 10.1016/S0022-5223(96)70250-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8751491-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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