Article
Modulation of the phenotypic diversity of sickle cell anemia.
Hemoglobin - 1 Feb 1996
Steinberg M H
Abstract excerpt
Sickle cell anemia is noted for being phenotypically heterogeneous. This suggests that there are genetic influences that moderate the effects of the sickle hemoglobin mutation. In this review I focus on genetically determined modulation of hemoglobin concentration and fetal hemoglobin levels. Eac...
Topics
- Anemia, Sickle Cell
- Fetal Hemoglobin
- Genetic Variation
- Humans
- Phenotype
- alpha-Thalassemia
