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Article

Alteration of haem-attachment and signal-cleavage sites for Paracoccus denitrificans cytochrome C550 probes pathway of c-type cytochrome biogenesis in Escherichia coli.

Molecular microbiology - 1 Mar 1996

Sambongi Y, Stoll R, Ferguson S J

Abstract excerpt

Paracoccus denitrificans cytochrome C550 is expressed as a periplasmic holo-protein in Escherichia coli; amino acid substitutions of cysteine residues in the haem-binding motif (Cys-X-X-Cys-His), either together or singly, prevented covalent attachment of haem but not polypeptide translocation into the periplasm. When the three alanine residues at positions -3 to -1 in the native signal-cleavage site were...

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Identifiers

PMID: 8730862
DOI: 10.1111/j.1365-2958.1996.tb02465.x

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Alteration of haem-attachment and signal-cleavage sites for Paracoccus denitrificans cytochrome C550 probes pathway of c-type cytochrome biogenesis in Escherichia coli.PMID 8730862Read ↗

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