Article
Allelic variation in the cagA gene of Helicobacter pylori obtained from Korea compared to the United States.
The American journal of gastroenterology - 1 Jul 1996
Miehlke S, Kibler K, Kim J G, Figura N, Small S M, Graham D Y, Go M F
Abstract excerpt
OBJECTIVE: Helicobacter pylori is an important factor in the development of duodenal ulcer disease and has been implicated in the pathogenesis of gastric adenocarcinoma. It has been suggested that the cagA gene is a marker for more virulent strains of H. pylori. METHODS: We determined the prevalence of the cagA gene in 60 clinical isolates [34 from gastric carcinoma patients (CA), 26 from duodenal ulcer patients...
Topics
- Adenocarcinoma
- Adult
- Aged
- Alleles
- Antigens, Bacterial
- Bacterial Proteins
- Base Sequence
- Duodenal Ulcer
- Female
- Genes, Bacterial
- Genetic Variation