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Article

Comparison of targeted-gene replacement frequencies in Drosophila melanogaster at the forked and white loci.

Molecular and cellular biology - 1 Jul 1996

Lankenau D H, Corces V G, Engels W R

Abstract excerpt

P element-induced gene conversion has been previously used to modify the white gene of Drosophila melanogaster in a directed fashion. The applicability of this approach of gene targeting in Drosophila melanogaster, however, has not been analyzed quantitatively for other genes. We took advantage of the P element-induced forked allele, f(hd), which was used as a target, and we constructed a vector containing a...

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Identifiers

PMID: 8668169
DOI: 10.1128/MCB.16.7.3535
PMCID: PMC231348

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