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Article

Altered expression of Pax-5 gene in human myeloma cells

15 May 1996

Abstract excerpt

Recent phenotypic analysis of plasma cells showed that normal plasma cells do express the B-cell lineage-specific molecule CD19, but their malignant counterpart (myeloma cells) are CD19-. To clarify the meaning of loss of CD19 antigen on myeloma cells, we first compared the expression of CD19 and Pax-5 genes among B cells, normal plasma cells, myeloma cell lines, and primary myeloma cells, because the Pax-5 gene...

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PMID: 8639790
DOI: 10.1182/blood.v87.10.4311.bloodjournal87104311

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