Article
Neonatal purpura fulminans in association with factor V R506Q mutation.
The Journal of pediatrics - 1 May 1996
Pipe S W, Schmaier A H, Nichols W C, Ginsburg D, Bozynski M E, Castle V P
Abstract excerpt
We report a case of neonatal purpura fulminans associated with activated protein C resistance. Analysis of DNA demonstrated heterozygosity for the factor V R506Q mutation. The neonate, at 8 hours of age, had progressive purpuric skin lesions and later had evidence of microvascular, hemorrhagic th...
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