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Article

Neonatal purpura fulminans in association with factor V R506Q mutation.

The Journal of pediatrics - 1 May 1996

Pipe S W, Schmaier A H, Nichols W C, Ginsburg D, Bozynski M E, Castle V P

Abstract excerpt

We report a case of neonatal purpura fulminans associated with activated protein C resistance. Analysis of DNA demonstrated heterozygosity for the factor V R506Q mutation. The neonate, at 8 hours of age, had progressive purpuric skin lesions and later had evidence of microvascular, hemorrhagic thrombosis in the brain. The baby was treated with fresh frozen plasma infusions and had complete resolution of the skin...

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Source

Identifiers

PMID: 8627449
DOI: 10.1016/s0022-3476(96)80142-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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