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The virion glycoproteins of Ebola viruses are encoded in two reading frames and are expressed through transcriptional editing.

16 Apr 1996

Abstract excerpt

In late 1994 and early 1995, Ebola (EBO) virus dramatically reemerged in Africa, causing human disease in the Ivory Coast and Zaire. Analysis of the entire glycoprotein genes of these viruses and those of other EBO virus subtypes has shown that the virion glycoprotein (130 kDa) is encoded in two reading frames, which are linked by transcriptional editing. This editing results in the addition of an extra...

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PMID: 8622982
DOI: 10.1073/pnas.93.8.3602

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