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Article

Genetic heterogeneity in isogenic homozygous clonal zebrafish.

Proceedings of the National Academy of Sciences of the United States of America - 19 Dec 1995

Buth D G, Gordon M S, Plaut I, Drill S L, Adams L G

Abstract excerpt

The C32 isogenic homozygous diploid (IHD) strain of the zebrafish (Danio rerio) was found to be polyallelic at a malate dehydrogenase locus (sMdh-A). A variant allele is thought to have arisen via mutation within the past 10 bisexual generations that have maintained the strain since its last gynogenetic cloning event; this unique allele now predominates at the sMdh-A locus. The estimated mutation rate in this...

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Identifiers

PMID: 8618902
DOI: 10.1073/pnas.92.26.12367
PMCID: PMC40358

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