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Article

Genetics of abnormal human fertilization

1 Oct 1995

Abstract excerpt

The purpose of this study was to assess the genetic status of abnormal zygotes following assisted fertilization. Dispermic, monopronucleated and digynic zygotes were allowed to cleave intact or after enucleation, and on the biopsied blastomeres, multiplex polymerase chain reaction and fluorescent in-situ hybridization were performed. It was found that the distal pronucleus was usually male in origin in dispermic...

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PMID: 8592028
DOI: 10.1093/humrep/10.suppl_1.120

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