Article
Complete structural organization of the human alpha 1 (V) collagen gene (COL5A1): divergence from the conserved organization of other characterized fibrillar collagen genes.
Genomics - 10 Oct 1995
Takahara K, Hoffman G G, Greenspan D S
Abstract excerpt
Genes that encode the vertebrate fibrillar collagen types I-III have previously been shown to share a highly conserved intron/exon organization, thought to reflect common ancestry and evolutionary pressures at the protein level. We report here the complete intron/exon organization of COL5A1, the...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Biological Evolution
- Cloning, Molecular
- Collagen
- Conserved Sequence
- DNA Primers
- Exons
- Genetic Variation
- Humans
- Introns
- Molecular Sequence Data
- Nucleic Acid Conformation
- Polymerase Chain Reaction
- Procollagen
- Restriction Mapping
- Vertebrates