Organization and expression of basement membrane collagen IV genes and their roles in human disorders.

doi:10.1093/oxfordjournals.jbchem.a022003

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Article

Organization and expression of basement membrane collagen IV genes and their roles in human disorders.

Journal of biochemistry - 1 May 1998

Sado Y, Kagawa M, Naito I, Ueki Y, Seki T, Momota R, Oohashi T, Ninomiya Y

Abstract excerpt

Six distinct genes have been identified as belonging to the type IV collagen gene family. They can be organized into three sets, i.e., COL4A1/COL4A2, COL4A3/COL4A4, and COL4A5/COL4A6, which are localized on three different chromosomes in humans, 13, 2, and X, respectively. Within each set the gen...

Topics

Amino Acid Sequence
Animals
Basement Membrane
Chromosomes, Human
Collagen
Gene Expression Regulation
Humans
Leiomyomatosis
Molecular Sequence Data
Mutation
Nephritis, Hereditary

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