Article
Patterns of immune responses to the host-encoded GOR and hepatitis C virus core-derived epitopes with relation to hepatitis C viremia, genotypes, and liver disease severity.
The Journal of infectious diseases - 1 Feb 1996
Quiroga J A, Pardo M, Navas S, Martín J, Carreño V
Abstract excerpt
Antibody responses to the GOR epitope and hepatitis C virus (HCV) core were investigated in 136 patients with chronic HCV infection. Patient age (P = .011) and necroinflammatory activity (P < .001) were significantly greater in 92 (67.6%) patients with anti-GOR than in 44 (32.4%) patients without...
Topics
- Adult
- Amino Acid Sequence
- Autoantibodies
- Autoantigens
- Chronic Disease
- Enzyme-Linked Immunosorbent Assay
- Epitopes
- Female
- Genotype
- Hepacivirus
- Hepatitis C
- Hepatitis C Antibodies
- Humans
- Liver
- Male
- Middle Aged
- Molecular Sequence Data
- Oligopeptides