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Genetic counselling and testing for susceptibility to breast, ovarian and colon cancer: where are we today?

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne - 15 Jan 1996

Cole D E, Gallinger S, McCready D R, Rosen B, Engel J, Malkin D

Abstract excerpt

Recent advances in our understanding of the genetic characteristics of cancer will change approaches to genetic screening and counselling. Cancer results from multiple, cumulative mutations in genes that regulate cell replication and differentiation. In familial cancer a germ-line mutation is passed on in an autosomal dominant pattern, but cancer will develop in people who inherit the defect only if other...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 8548703
PMCID: PMC1488145

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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