Article
Immunohistochemical and serological evaluation of CD44 splice variants in human ovarian cancer.
British journal of cancer - 1 Dec 1995
Sliutz G, Tempfer C, Winkler S, Kohlberger P, Reinthaller A, Kainz C
Abstract excerpt
The surface glycoprotein CD44 is widely distributed in different tissues. In contrast to healthy tissue, tumour samples show a more complex pattern of CD44 expression, indicating a loss of splice control. Beside cell-surface expression, the measurement of soluble CD44 in serum of cancer patients could be useful in early diagnosis and assessment of disease status. We evaluated the surface expression of CD44...
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