Article
Analysis of the evolution and variation of the human influenza A virus nucleoprotein gene from 1933 to 1990.
Journal of virology - 1 May 1993
Shu L L, Bean W J, Webster R G
Abstract excerpt
This study examined the evolution and variation of the human influenza virus nucleoprotein gene from the earliest isolates to the present. Phylogenetic reconstruction of the most parsimonious evolutionary path connecting 49 nucleoprotein sequences yielded a single lineage. The average calculated...
Topics
- Amino Acid Sequence
- Animals
- Biological Evolution
- Cells, Cultured
- Chick Embryo
- Cloning, Molecular
- Genes, Viral
- Genetic Variation
- Influenza A virus
- Molecular Sequence Data
- Mutagenesis
- Nucleocapsid Proteins
- Nucleoproteins
- Polymerase Chain Reaction
- Sequence Analysis, DNA
- Sequence Homology, Amino Acid
- Time Factors
- Viral Core Proteins