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Article

Analysis of the evolution and variation of the human influenza A virus nucleoprotein gene from 1933 to 1990.

Journal of virology - 1 May 1993

Shu L L, Bean W J, Webster R G

Abstract excerpt

This study examined the evolution and variation of the human influenza virus nucleoprotein gene from the earliest isolates to the present. Phylogenetic reconstruction of the most parsimonious evolutionary path connecting 49 nucleoprotein sequences yielded a single lineage. The average calculated rate of mutation was 3.6 nucleotide substitutions per year (2.3 x 10(-3) substitutions per site per year). Thirty-two...

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Identifiers

PMID: 8474171
DOI: 10.1128/JVI.67.5.2723-2729.1993
PMCID: PMC237595

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