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Article

Prospects for estimating nucleotide divergence with RAPDs.

Molecular biology and evolution - 1 Sept 1993

Clark A G, Lanigan C M

Abstract excerpt

The technique of random amplification of polymorphic DNA (RAPD), which is simply polymerase chain reaction (PCR) amplification of genomic DNA by a single short oligonucleotide primer, produces complex patterns of anonymous polymorphic DNA fragments. The information provided by these banding patterns has proved to be of great utility for mapping and for verification of identity of bacterial strains. Here we...

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PMID: 8412651
DOI: 10.1093/oxfordjournals.molbev.a040057

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