Article
Sucrase-isomaltase gene expression in Barrett's esophagus and adenocarcinoma.
Gastroenterology - 1 Sept 1993
Wu G D, Beer D G, Moore J H, Orringer M B, Appelman H D, Traber P G
Abstract excerpt
BACKGROUND: Specialized Barrett's esophageal mucosa, characterized by incomplete intestinal metaplasia of the esophageal mucosa, is associated with the development of adenocarcinoma. Although the intestinal disaccharidase sucrase-isomaltase (SI) has been shown in incomplete intestinal metaplasia of the stomach, it is commonly believed that Barrett's mucosa does not express SI based on the lack of enzymatic...
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