Two different, adjacent and divergent zinc finger binding sites are necessary for CREA-mediated carbon catabolite repression in the proline gene cluster of Aspergillus nidulans.

Abstract excerpt

CREA is the negative regulator mediating carbon catabolism repression in Aspergillus nidulans. We have determined all the sites in the DNA region between the prnD and prnB genes of the proline degradation cluster of this organism which are able to bind a fusion protein containing the zinc finger...

Topics

• Aspergillus nidulans
• Base Sequence
• Binding Sites
• DNA, Fungal
• Fungal Proteins
• Gene Expression Regulation, Fungal
• Genes, Fungal
• Introns
• Molecular Sequence Data
• Multigene Family
• Mutation
• Proline
• Repressor Proteins
• Zinc Fingers