Article
Evidence of genetic and phenotypic heterogeneity in the Romano-Ward syndrome.
Journal of medical genetics - 1 Nov 1993
Dean J C, Cross S, Jennings K
Abstract excerpt
We report two families with phenotypically different forms of Romano-Ward syndrome. In one family, only five of 18 affected subjects are symptomatic, whereas in the other the proportion is three out of five. The families show distinct ECG morphologies, in addition to QT prolongation. Previous reports have shown genetic linkage either to the HLA locus on chromosome 6 or the Harvey-ras oncogene on chromosome 11. No...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.