Evidence of genetic and phenotypic heterogeneity in the Romano-Ward syndrome.

doi:10.1136/jmg.30.11.947

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Article

Evidence of genetic and phenotypic heterogeneity in the Romano-Ward syndrome.

Journal of medical genetics - 1 Nov 1993

Dean J C, Cross S, Jennings K

Abstract excerpt

We report two families with phenotypically different forms of Romano-Ward syndrome. In one family, only five of 18 affected subjects are symptomatic, whereas in the other the proportion is three out of five. The families show distinct ECG morphologies, in addition to QT prolongation. Previous rep...

Topics

Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 6
Electrocardiography
Female
Genetic Linkage
Genotype
Humans
Long QT Syndrome
Male
Pedigree
Phenotype

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