Article
Wegener's granulomatosis and Henoch-Schönlein purpura in a family with hereditary C4 deficiency.
Advances in experimental medicine and biology - 1 Jan 1993
Lhotta K, Kronenberg F, Joannidis M, Feichtinger H, König P
Abstract excerpt
Described here is a family in which the father with partial C4 deficiency had Wegener's granulomatosis and a son with complete C4 deficiency presented with Henoch-Schönlein Purpura. The possible role of C4 deficiency in the pathogenesis of both vasculitic disorders is discussed.
Topics
- Adolescent
- Complement C4
- Granulomatosis with Polyangiitis
- HLA Antigens
- Haplotypes
- Humans
- IgA Vasculitis
- Male
- Middle Aged
- Phenotype