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Article

Inter- and intra-strain genomic variation in equine herpesvirus type 1 isolates.

Archives of virology - 1 Jan 1994

Bonass W A, Hudson W A, Elton D M, Killington R A, Halliburton I W

Abstract excerpt

Restriction enzyme digests of DNA from 22 unselected isolates of EHV-1 were analysed by hybridization with cloned DNA fragments covering the genome. In addition to a small amount of inter-strain variation, heterogeneity within strains was observed, caused by loss of specific restriction endonuclease sites in the DNA of a proportion of the virus particles of any one stock. Fifteen strains demonstrated the same...

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PMID: 8279952
DOI: 10.1007/BF01379115

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