Article
Phosphoglucomutase 1: a gene with two promoters and a duplicated first exon.
The Biochemical journal - 1 Dec 1993
Putt W, Ives J H, Hollyoake M, Hopkinson D A, Whitehouse D B, Edwards Y H
Abstract excerpt
In view of its central role in glycolysis and gluconeogenesis and its polymorphic genetic variability, the phosphoglucomutase 1 (PGM1) gene in man has been the target of protein structural studies and genetic analysis for more than 25 years. We have now isolated genomic clones containing the comp...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA Primers
- DNA Probes
- Exons
- Genomic Library
- Hominidae
- Humans
- Introns
- Isoenzymes
- Molecular Sequence Data
- Multigene Family
- Muscles
- Mutation
- Phosphoglucomutase
- Polymerase Chain Reaction
- Promoter Regions, Genetic