Article
Analysis of astrovirus serotype 1 RNA, identification of the viral RNA-dependent RNA polymerase motif, and expression of a viral structural protein.
Journal of virology - 1 Jan 1994
Lewis T L, Greenberg H B, Herrmann J E, Smith L S, Matsui S M
Abstract excerpt
We report the results from sequence analysis and expression studies of the gastroenteritis agent astrovirus serotype 1. We have cloned and sequenced 5,944 nucleotides (nt) of the estimated 7.2-kb RNA genome and have identified three open reading frames (ORFs). ORF-3, at the 3' end, is 2,361 nt in...
Topics
- Amino Acid Sequence
- Base Sequence
- Cells, Cultured
- Cloning, Molecular
- Genetic Variation
- Humans
- Mamastrovirus
- Molecular Sequence Data
- Nucleic Acid Conformation
- Open Reading Frames
- RNA, Viral
- RNA-Dependent RNA Polymerase
- Sequence Analysis, DNA
- Sequence Homology, Amino Acid