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Article

Rad: a Member of the Ras Family Overexpressed in Muscle of Type II Diabetic Humans

26 Nov 1993

Abstract excerpt

To identify the gene or genes associated with insulin resistance in Type II (non-insulin-dependent) diabetes mellitus, subtraction libraries were prepared from skeletal muscle of normal and diabetic humans and screened with subtracted probes. Only one clone out of 4000 was selectively overexpressed in Type II diabetic muscle as compared to muscle of non-diabetic or Type I diabetic individuals. This clone encoded...

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PMID: 8248782
DOI: 10.1126/science.8248782

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Source receipt: pubmed, retrieved 7 Sept 2026.

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